Research Assistant, Warren Center for Neuroscience Drug Discovery

Full Time
Franklin, TN 37067
Posted
Job description
This position is part of the Warren Center for Neuroscience Drug Discovery (WCNDD) at Vanderbilt University where traditional academic pursuits in basic science are extended to advance our understanding of human disease and drug targets to directly impact patient care.
The position calls for a motivated biological scientist to join the Molecular Pharmacology group within the WCNDD. The Pharmacology team is responsible for conducting high-throughput screening assay of small molecule modulators of GPCRs, ion channels, and kinases. This includes development of target protein cell lines and secondary pharmacological assay to support all molecular pharmacology activities. This position is a key contributor to support the Center’s goal of developing therapeutics, specifically for central nervous system disorders. Successful candidates will interface with members among all areas of the WCNDD, including those in molecular pharmacology, medicinal chemistry, drug metabolism and pharmacokinetics, and in vivo rodent pharmacology.

Duties and Responsibilities:

We are all different, yet we all use our unique contributions to serve patients. The Molecular Pharmacology Research Assistant we seek is a person with these qualifications.

  • Perform in vitro pharmacological experiments independently or as a part of team.
  • Conduct high-throughput screening assays using fluorescent-based plate kinetic readers in support of characterizing GPCR-targeted small molecule drugs.
  • Conduct high-throughput TR-FRET screening assays in support of developing selective kinase inhibitors.
  • Maintain mammalian cell lines used in the screening assays.
  • Develop stable cell lines specific to new target proteins.
  • Prepare DNA/RNA and Protein samples and analyze in routine molecular biology assay.
  • Operate multi forms of liquid handling equipment, and automation units.
  • Understand and follow pharmacological assay protocols applicable to assigned tasks.
  • Analyze data to determine the efficacy and potency of the compounds using data analysis software.
  • Maintains accurate databases and experimental notebooks of results.

Qualifications

  • Bachelor’s degree in biology, biochemistry, pharmacology, or related field of study is necessary.
  • 1-2 years’ experience with a minimum of 1 year of mammalian cell culture experience is necessary.
  • Hands-on experience of plasmid preparation, transfection, and Western Blotting.
  • Excellent oral and written communication skills
  • Good documentation practices with excellent organization and attention to detail
  • Self-motivated team player with the ability to thrive in a fast paced, dynamic, multi-disciplinary, matrixed environment.
Commitment to Equity, Diversity, and Inclusion
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.
Vanderbilt University is an equal opportunity, affirmative action employer. Women, minorities, people with disabilities and protected veterans are encouraged to apply.
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.
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Vanderbilt is a community of talented and diverse staff & faculty!

At Vanderbilt University , our work - regardless of title or role - is in service to an important and noble mission in which every member of our community serves in advancing knowledge and transforming lives on a daily basis. Located in Nashville , Tennessee, on a 330+ acre campus and arboretum dating back to 1873, Vanderbilt is proud to have been named as one of “America’s Best Large Employers” as well as a top employer in Tennessee and the Nashville metropolitan area by Forbes for several years running. We welcome those who are interested in learning and growing professionally with an employer that strives to create, foster and sustain opportunities as an employer of choice through:

  • Working and growing together as a community of communities... we are One Vanderbilt .
  • Providing a work environment where every staff and faculty member can be their authentic and best self , while providing the resources and opportunities to learn and grow.
  • Encouraging development, collaboration, and partnership both internally and externally while fostering the value that every member of the Vanderbilt community can lead and grow regardless of title or position.

We understand you have a choice when choosing where to work and pursue a career. We understand you are unique and have a story. We want to hear it. We encourage you to apply today so that you might become a part of our story.

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Vanderbilt University has made the health and safety of our students, faculty and staff and our surrounding communities a top priority. As part of that commitment, the University may require employees to comply with any testing or health and safety measures which the University may require.

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