Summary

The Department of Pathology is seeking an experienced biologist to serve as a lab manager and research technician for the laboratory of Dr. Russell Ryan, MD. In addition to general lab management responsibilities, the successful applicant will assist in projects related to functional genomics and transcriptional regulation in lymphoid malignancies. The Ryan Lab utilizes cutting-edge tools for the genome-wide analysis of enhancer function and regulation in normal and malignant lymphocytes.

Work will be performed at the Ryan lab, which was established in July 2017. The lab is primarily affiliated with the University of Michigan Department of Pathology, and is located in the Rogel Cancer Center building in the U-M Medical Campus.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Responsibilities*

Biological research technician duties (70% of time) may include:

• Mammalian cell culture
• Basic molecular biology techniques (plasmid preparation, cloning, mutagenesis)
• Maintaining mouse colonies (patient-derived leukemia mouse models)
• Lentivirus production and use for genetic manipulation of cell lines
• Targeted genome editing or manipulation (CRISPR-Cas9 system)
• Chromatin immunoprecipitation of histone marks and transcription factors (ChIP-Seq)
• Next-generation sequencing library preparation and data production
• Retrieving and processing human lymphoma samples from tissue or blood.

Lab manager duties (30% of time) will include:

• Ordering, organizing and inventorying research equipment and materials
• Scientific and administrative record-keeping
• Personnel on-boarding and off-boarding

All work and data must be meticulously recorded and organized

Required Qualifications*

BA or BS, with a concentration in the biological sciences and one to two years of research laboratory experience, pre- or post-graduation

? The ideal candidate will be a highly motivated individual interested in a career in biological research or medicine

? Technically meticulous when conducting experiments

? Highly organized in record-keeping

? Strong communication and interpersonal skills

? Independent, intellectually passionate and able to display scientific initiative

?

Desired Qualifications*

Experience in mammalian cell culture and basic molecular biology techniques strongly preferred.

Experience in computational data analysis (Linux, Python, R) is desirable and may qualify the applicant for the higher level of the job classification.

Underfill Statement

This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

Vaccine Requirements

COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute. This includes those working remotely and temporary workers. More information on this new policy is available on the U-M Health Response.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.